Is Treatment with Trimetazidine Beneficial in Patients with Chronic Heart Failure?
نویسندگان
چکیده
منابع مشابه
Is Treatment with Trimetazidine Beneficial in Patients with Chronic Heart Failure?
BACKGROUND Whether additional benefit can be achieved with the use of trimetazidine (TMZ) in patients with chronic heart failure (CHF) remains controversial. We therefore performed a meta-analysis of randomized controlled trials (RCTs) to evaluate the effects of TMZ treatment in CHF patients. METHODS We searched PubMed, EMBASE, and Cochrane databases through October 2013 and included 19 RCTs ...
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The possibility of modifying cardiac metabolism by switching the fuel used by the myocardium could become increasingly important, especially in clinical conditions characterized by reduced energy availability, such as heart failure. Trimetazidine (VastarelMR), an inhibitor of free fatty acid (FFA) oxidation, holds the characteristics to play a fundamental role in the therapeutic strategy of pat...
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The aim of the study was to assess whether trimetazidine (TMZ) could affect dispersion of atrial depolarization and ventricular repolarization. Corrected QT interval (QTc), QTc dispersion (QTc-d), Tpeak-Tend, and Tpeak-Tend dispersion (Tpeak-Tend-d) were measured in 30 patients with chronic heart failure (CHF) before and 6 months after randomization to conventional therapy plus TMZ (17 patients...
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چکیده ندارد.
15 صفحه اولAdditional use of trimetazidine in patients with chronic heart failure: a meta-analysis.
OBJECTIVES The aim of this meta-analysis was to evaluate the effects of additional trimetazidine (TMZ) treatment on patients with chronic heart failure (CHF). BACKGROUND Conflicting results currently exist on the clinical use of TMZ in CHF patients. METHODS PubMed, MEDLINE, EMBASE, and EBM Reviews databases were searched through November 2010 for randomized controlled trials (RCTs) assessin...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2014
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0094660